Here’s What DNA Really Looks Like

Here's What DNA Really Looks Like

There’s more to DNA than just the double helix we know and love: under some conditions this familiar molecule can take on unfamiliar forms, each of which can have a different impact on our health.

Hosted by: Hank Green

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Sources:
General overviews of alternate DNA structures:
https://www.intechopen.com/books/dna-replication-current-advances/dna-structure-alphabet-soup-for-the-cellular-soul
https://www.ncbi.nlm.nih.gov/books/NBK6545/

Click to access dnastructure.pdf

B-DNA and history of the double helix:
https://www.nature.com/scitable/topicpage/discovery-of-dna-structure-and-function-watson-397/

A-DNA:

Click to access a00979.pdf

Z-DNA:
https://www.nature.com/articles/s42003-018-0237-x

H-DNA:

Click to access 13448.full.pdf

G-quadruplexes:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516791/

Image Sources:
https://commons.wikimedia.org/wiki/File:Base_pair_GC.svg
https://commons.wikimedia.org/wiki/File:Base_pair_AT.svg
https://commons.wikimedia.org/wiki/File:DNA_orbit_animated.gif
https://commons.wikimedia.org/wiki/File:A-DNA_orbit_animated.gif
https://commons.wikimedia.org/wiki/File:Z-DNA_orbit_animated.gif
https://www.istockphoto.com/vector/dna-gm477462523-36133444
https://www.istockphoto.com/photo/chromatin-strand-and-isolated-nucleosome-dna-histones-gm1169905740-323575931
https://commons.wikimedia.org/wiki/File:A-B-Z-DNA_Side_View.png


https://commons.wikimedia.org/wiki/File:0323_DNA_Replication.jpg
https://commons.wikimedia.org/wiki/File:DNA_replication_split.svg
https://www.istockphoto.com/photo/abstract-glittering-dna-helix-with-depth-of-field-over-dark-space-background-gm1201193016-344376611
https://commons.wikimedia.org/wiki/File:TriplexDNA(1BWG).png
https://www.istockphoto.com/photo/the-fracture-of-dna-molecular-gm450571643-24790953
https://www.istockphoto.com/photo/illustration-of-a-damaged-ribonucleic-acid-or-dna-strand-gm923218260-253424716
https://www.istockphoto.com/photo/yellow-and-blue-shoelace-gm120499022-15977723
https://www.istockphoto.com/photo/telomere-gm670202484-122541287
https://www.istockphoto.com/photo/chromosomes-gm173851340-8968775
https://commons.wikimedia.org/wiki/File:Guanin.svg
https://commons.wikimedia.org/wiki/File:G-quadruplex.svg
https://commons.wikimedia.org/wiki/File:Telomer-structure.gif
https://commons.wikimedia.org/wiki/File:Basic_units_of_chromatin_structure.svg
https://commons.wikimedia.org/wiki/File:Cytosin.svg
https://commons.wikimedia.org/wiki/File:RNA_i-motif.gif
https://commons.wikimedia.org/wiki/File:Holliday_junction_coloured.png

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